Endocrine Abstracts

Objective: Describe clinical, laboratorial, imaging features, therapeutic management and the outcomes of patients with clinically non-functioning pituitary adenomas (NFPAs) presenting at our department.Methods: Retrospective review of electronic medical records of all patients with NFPAs evaluated at our department between 2010 and 2019.Results: We evaluated 160 patients, 51.3% female, with a median age of 56.6 years (18–89). ...

Aim: Acromegaly is associated with premature dead and a number of risk factors for cardiovascular disease (CVD). We aimed to examine the concept of cumulative GH exposure with regard to the presence these risk factors and cancer in acromegalic patients.Methods: Retrospective observational study in all acromegalic patients from 2006 to 2017 with a minimum of 3 years of follow-up. We exclude patients not treated. GH exposure was calculated as median GH or ...

Introduction: Pituitary tumours are considered benign, however some exhibit an aggressive behavior. Defining a timely treatment is challenging due to absence of accurate prognostic predictors.Objective: To evaluate radiological and histopathological features of aggressive pituitary tumours.Methods: Multicenter and retrospective study. Criteria for aggressiveness were: invasion to sphenoid and/or cavernous sinus; growth progression ...